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COV-BOOST national vaccination trial at Addenbrooke’s

A team from Cambridge is inviting individuals aged 18 to 30 years to enrol in a national vaccination trial (COV-BOOST) which is assessing the use of lower doses of 2 approved vaccines for COVID-19: BNT162b2 – (Pfizer) and mRNA-1273 (Moderna) when given to young adults as a 3rd or 4th dose booster vaccine. You’d be randomised to receive a booster dose of COVID-19 vaccine (Pfizer or Moderna) at either full or “fractional” dosage in the Clinical Research Facility at Addenbrooke’s Hospital during a few dates in October.

If immune responses to full and fractional doses are equivalent, this study may change COVID-19 vaccination schedules both in the UK and internationally – with the use of reduced vaccine dosage providing the potential to greatly increase the availability of COVID mRNA vaccines worldwide, including developing nations. More information about taking part in the trial

Once you arrive in Cambridge, we recommend that you register with a local GP surgery. You can find more information about local practices or speak to your College if you need help to register with a GP. If you have any questions about the information on our physical health pages, please contact the Communicable Disease Helpdesk via email or telephone: 01223 339514.

COV-BOOST national vaccination trial at Addenbrooke’s

A team from Cambridge is inviting individuals aged 18 to 30 years to enrol in a national vaccination trial (COV-BOOST) which is assessing the use of lower doses of 2 approved vaccines for COVID-19: BNT162b2 – (Pfizer) and mRNA-1273 (Moderna) when given to young adults as a 3rd or 4th dose booster vaccine. You’d be randomised to receive a booster dose of COVID-19 vaccine (Pfizer or Moderna) at either full or “fractional” dosage in the Clinical Research Facility at Addenbrooke’s Hospital during a few dates in October.

If immune responses to full and fractional doses are equivalent, this study may change COVID-19 vaccination schedules both in the UK and internationally – with the use of reduced vaccine dosage providing the potential to greatly increase the availability of COVID mRNA vaccines worldwide, including developing nations.

If you are interested in taking part, further information is available on the COV-Boost website.